Chile advanced to the Copa America quarter-finals after two goals in the first half from Eduardo Vargas and two in the second from Alexis Sanchez gave them a 4-2 win over Panama, while Argentina took top spot by beating Bolivia 3-0 in Group D.

Defending champions Chile will play Mexico in the next round on Saturday with Argentina facing Venezuela the same day.

Chile went behind to an early goal but roared back thanks to outstanding performances from their front pair, who ran the Panamanian defence ragged.

Panama took the lead after a mistake by goalkeeper Claudio Bravo, who let Miguel Camargo’s shot from almost 30 yards squirm through his hands and into the net.

Chile fought back and were soon 2-1 up.

Arturo Vidal and Sanchez worked a one-two in the box and Sanchez’s shot was only parried by Jaime Penedo and Vargas followed up to smash it home.

Three minutes before half-time striker Vargas rose to glance home a header to put Chile ahead.

Sanchez was in captivating form and scored one of the goals of the tournament after 49 minutes.

Vargas was the provider this time, creating space for himself in the box before chipping to Sanchez, who volleyed home in spectacular fashion.

Panama kept fighting and pulled one back and again Bravo was at fault, failing to stop Abdiel Arroyo’s header from going in at his near post.

Sanchez had the last word, however, when he headed home with two minutes left to make it 4-2.

In Seattle, few were expecting anything other than an Argentine win over Bolivia and most of the attention was focused on whether Lionel Messi would surpass Gabriel Batistuta’s record of 54 goals for his country.

Needing one to tie the mark, Messi came on as a second-half substitute with his team 3-0 up through Erik Lamela, Ezequiel Lavezzi and Victor Cuesta.

The closest Messi came to scoring was from a free-kick but his curled effort sailed just wide.

The Quarter-finals

United States vs Ecuador; Peru vs Colombia; Argentina vs Venezuela; Mexico vs Chile.