Chelsea suffered a heavy blow in their late-season push for a Champions League spot when they were held to a 1-1 draw at home to struggling Huddersfield Town in the Premier League on Wednesday.
Huddersfield, who needed a point to be sure of avoiding relegation, took a shock lead in the 50th minute when a long ball from Aaron Mooy found Laurent Depoitre who won a challenge with Chelsea goalkeeper Willy Caballero on the edge of the box and put the ball in the empty net.
It was Huddersfield's first attempt on goal and Chelsea were back level 13 minutes later when a defensive clearance struck Marcos Alonso on the head and rebounded into the net.
Chelsea kept up the pressure as they pushed for a winner and Huddersfield keeper Jonas Lossl turned a header by Andreas Christensen on to the post.
But the visitors held on to secure their Premier League status and Chelsea remained outside the Champions League spots in fifth place with one game left in the season.
Tottenham Hotspur's England striker Harry Kane struck early in the second half to secure a 1-0 win over Newcastle United and ensure a top-four Premier League finish and Champions League qualification for next season.
With Chelsea held by Huddersfield, Tottenham's win left them four points clear of their London rivals with one round of games remaining this season.
Kane struck five minutes into the second half with a precise finish from inside the area after being fed by Son Heung-min to relieve the tension that had built up inside Wembley Stadium.
Newcastle almost scored early in the first half when Jonjo Shelvey's free kick clipped the post but Spurs improved after the break and Kane grabbed his 28th league goal of the season.
Leicester striker Jamie Vardy scored his sixth goal in as many Premier League games against Arsenal to help them to a 3-1 home win over the London club, who were reduced to 10 men in the first half.
Vardy converted a 76th-minute penalty and Riyad Mahrez sealed Leicester's win after Arsenal striker Pierre-Emerick Aubameyang had cancelled out Kelechi Iheanacho's 14th-minute opener for the home side.
Yaya Toure bade farewell to the Etihad Stadium as champions Manchester City set a hat-trick of Premier League records in a routine 3-1 win over Brighton.
Veteran midfielder Toure was made captain for his final home appearance and goals from Danilo, Bernardo Silva and Fernandinho, cancelling out a Leonardo Ulloa effort, ensured he finished on the winning side.
Records tumbled as City took their goals tally for the campaign to 105, their points total to 97 and their number of wins to 31, eclipsing previous best marks set by Chelsea.