Serie A leaders Napoli's title hopes suffered a setback when they collapsed to a 4-2 defeat at home to Roma on Saturday.

Napoli saw their own 10-match winning run in Serie A ended by two goals from Edin Dzeko and one apiece from Cengiz Under and Diego Perotti.

Napoli, beaten for only the second time this season in the league, lead with 69 points from 27 games but Juve are only one behind and, crucially, have a game in hand at home to Atalanta on March 14, the fixture having been snowed off last Sunday.

Roma were helped by another outstanding performance from Brazil goalkeeper Alisson who made a series of saves at important moments with Lorenzo Insigne his chief victim.

Napoli, playing after the Juventus game had finished, got off to a flying start when Insigne put them ahead after six minutes but Under levelled one minute later with a deflected shot which flew over Pepe Reina.

Dzeko put Roma ahead with a looping header from Alessandro Florenzi's cross in the 26th minute and the Bosnia forward added the third in the 73rd minute when he cut inside his marker and curled a shot beyond Reina's reach.

In doing so, he become the first player to score at least 50 goals in three of the top-five leagues in Europe -- 66 in the Bundesliga, 50 in the Premier League and 50 in Serie A.

It became a rout when Perotti fired home six minutes later, taking full advantage of a poor clearance by Mario Rui, although Dries Mertens made the score more respectable in stoppage time, finding the net with a low drive from outside the area.