Updated 9.15pm

Iran will remain committed to a multinational nuclear deal as long at it serves the country's national interests, and its ballistic missile programme will expand despite pressure from the United States, Iranian President Hassan Rouhani said today.

Responding to US President Donald Trump's speech earlier in which he said he would not continue to certify the multinational agreement, Rouhani said in a live televison address that it was full of "insults and fake accusations" against Iranian.

"The Iranian nation has not and will never bow to any foreign pressure...Iran and the deal are stronger than ever ... Iran's Islamic Revolutionary Guards Corps will continue its fight against regional terrorists," Rouhani said.

He added that Trump's decision to decertify the deal would isolate the United States as other signatories of the accord remained committed to it. The deal was not renegotiable, he said.

The speech generated strong reactions from around the world. The United States could not unilaterally cancel the 2015 nuclear deal between Iran and world powers, EU foreign policy chief Federica Mogherini said today in reaction to Trump's decision not to certify the accord.

"We cannot afford as the international community to dismantle a nuclear agreement that is working," said Mogherini, who chaired the final stages of the landmark talks.

"This deal is not a bilateral agreement ... The international community, and the European Union with it, has clearly indicated that the deal is, and will, continue to be in place," Mogherini told reporters.

Mogherini said she spoke to US Secretary of State Rex Tillerson immediately after Trump's speech today.

in the meantime, Israel's intelligence minister said Trump's speech against the 2015 international nuclear deal with Iran on Friday was "very significant" and could lead to war given threats that preceded it from Tehran.

Israel's Channel 2 TV asked Intelligence Minister Israel Katz whether he saw a risk of war after Trump's speech.

"Absolutely, yes. I think that the speech was very significant," Katz responded. "Iran is the new North Korea. We see where things are goings."

Russia's foreign ministry said Trump imposed unilateral sanctions on Iranand that there was no place in international diplomacy for threatening and aggressive rhetoric, adding that such methods were doomed to fail.

The ministry said in a statement Trump's decision to de-certify an international deal on Iran's nuclear program would not have a direct impact on implementation of the agreement, but that it ran counter to its spirit.

The ministry said that, whatever the US position, there could be no return to imposing United Nations sanctions on Iran.

The US military said  it was reviewing the "entire breadth" of its security cooperation activities, force posture and plans to support Trump's new strategy on Iran.

"We are identifying new areas where we will work with allies to put pressure on the Iranian regime, neutralise its destabilising influences, and constrain its aggressive power projection, particularly its support for terrorist groups and militants," Major Adrian Rankine-Galloway, a Pentagon spokesman, told Reuters.

Trump struck a blow against the 2015 Iran nuclear agreement today in defiance of other world powers, choosing not to certify that Tehran is complying with the deal and warning he might ultimately terminate it.

[Trump] gave the US Congress 60 days to decide whether to reimpose economic sanctions on Tehran that were lifted under the pact.

Trump announced the major shift in US policy in a speech that detailed a more confrontational approach to Iran over its nuclear and ballistic missile programs and its support for extremist groups in the Middle East.

Trump said in an address at the White House that his goal was to ensure Iran's never obtains a nuclear weapon.

"We will not continue down a path whose predictable conclusion is more violence more terror and the very real threat of Iran’s nuclear breakout," Trump said.

While Trump did not pull the United States out of the agreement, aimed at preventing Iran from developing a nuclear bomb, he gave the US Congress 60 days to decide whether to reimpose economic sanctions on Tehran that were lifted under the pact.

That would increase tension with Iran as well as put Washington at odds with other signatories of the accord such as Britain, France, Germany, Russia, China and the European Union.

Trump warned that if "we are not able to reach a solution working with Congress and our allies, then the agreement will be terminated."

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