U.S. investigators led by the FBI are poring over video and photographs from the widely watched Boston Marathon for clues to determine who is responsible for two bombs that exploded near the finish line, killing three people and injuring more than 100, officials said.

Because the Boston Marathon is run by 27,000 people and some 500,000 come to watch every year, officials expect plenty of visual evidence into what happened before and after two devices exploded as hundreds of runners streamed to the finish line at Copley Plaza in Boston's Back Bay neighbourhood.

The Federal Bureau of Investigation is heading the investigation with help from city, state and federal officials, FBI Special Agent Richard DesLauriers said at an evening news conference.

"It is a criminal investigation that is a potential terrorist investigation," he said, while declining to elaborate on initial findings or where the probe was headed.

But beyond being sure that bombs went off, there is little certainty yet about who might have been behind the attacks or what their motives might have been, although officials said the circumstances of the blasts suggested theories involving Islamic militants or U.S. anti-government extremists.

As of Monday evening, no agency had found any evidence that there was any obvious warning of the attack, nor has any claim of responsibility for the attacks surfaced. "There were no known threats," Boston Police Commissioner Ed Davis said.

Video played continually on Boston's local television stations showing rescuers racing to the injured and then carrying bloodied runners and spectators away as photographers captured the scene.

Davis said officials were reviewing the photographic evidence and asked the public to call with tips if they had seen anything suspicious.

In the meantime police are sweeping the entire 26.2-mile (42-km) route of the race for possible clues and have cordoned off the area around the blasts in the heart of Boston's shopping district.

A Justice Department official confirmed that Attorney General Eric Holder had talked about the case with FBI Director Robert Mueller and Boston U.S. Attorney Carmen Ortiz. The National Guard has been deployed and local hospitals are being guarded by armed police.

As Davis met with Boston Mayor Tom Menino, Massachusetts Governor Deval Patrick and other elected officials in a nearby hotel to brief the media, investigators were already poring over pictures shot by professionals and amateurs.

CIA JOINS INVESTIGATION

Police have told people, including the thousands of visitors who came to participate in Boston's signature sporting event, to stay inside and not congregate in open spaces. "Boston will be open tomorrow but it won't be business as usual," Patrick said.

In addition to domestic law enforcement, intelligence agencies such as the CIA and the National Counter-terrorism Center have joined the investigation.

At least two, essentially contradictory, theories about who might be behind the explosions were under immediate consideration by investigators, officials told Reuters on the condition of anonymity.

One theory, based at least in part upon the timing of the bombings - on the day when U.S. tax returns are due and also on the day of the Boston Marathon, which is customarily held on Patriots' Day - implies that domestic right-wing extremists, such as anti-government anti-tax activists, could be behind the attacks.

One of the main alternative theories, which was commended to Reuters by senior law enforcement officials, is that there could be some kind of connection, whether direct or very loose, to Islamic militants.

The principal evidence for this theory, the officials said, is what they say are similarities between what is known about the attacks - for example two simultaneous explosions in close proximity to each other at a high-profile event - to attack models proposed by Inspire magazine.

Inspire is a publication, circulated over the Internet, by Yemen-based al Qaeda in the Arabian Peninsula. The magazine publishes English-language exhortations to would-be Western jihadists to carry out attacks with whatever means, however modest, they have at hand. Inspire also recently published a lengthy supplement with detailed instructions on how to carry out various attacks and build home-made devices.

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