Two men from Naxxar were hospitalised what their car crashed and overturned in Mannarino Road, Birkirkara.
The incident happened at about 3.15pm.
The car was being driven towards Birkirkara when the driver lost control at a bend close to the VAT offices.
The vehicle smashed through railings and traffic signs and rolled over onto a road which also serves as a water channel some two metres below. A parked car was also damaged.
The police said the 26-year-old driver was slightly injured. A 34-year-old passenger suffered grievous injuries.