AS Roma captain Francesco Totti, who has only just returned to fitness after a thigh problem, will miss Sunday's league game at Reggina with a sore back, the club said.
Julio Baptista, John Arne Riise and Simone Perrotta also miss out alongside long-term injury victim Marco Cassetti and want-away defender Christian Panucci.
AS Roma have taken Mali defender Souleymane Diamoutene on loan from Lecce with a view to a permanent deal, the two Serie A clubs said in statements.