Senglea Bocci Club, the reigning champions, were eliminated in the quarter-finals of the knockout competition for teams, organised by the Malta Pool Association.
Hibs Pavilion reached the semi-finals after beating Senglea 19-8.
Cup holders Taste Good also went down to Top Gun with a disappointing 19-5 score.
Jesmond Sporting Club had the better of town rivals Hamrun Liberty ASC 19-14 and in the much-awaited fourth quarter-final, Espadon had to fight back to win the decisive frame and match by 19-18 against cup contenders San Gwann Bocci Club.
In this week's semi-finals, Hibs Pavilion face Espadon while Top Gun play against Jesmond SC.