League Cup holders Manchester United will start their bid to retain the trophy against Wolves in the third round at Old Trafford. Alex Ferguson's side were paired with the newly-promoted Premier League club in yesterday's draw.
Elsewhere fallen giants Leeds United, currently playing in League One, host Liverpool in the tie of the round. Chelsea face west London neighbours QPR and Arsenal are at home to West Bromwich Albion.
Manchester City take on Fulham, Sunderland play Birmingham, West Ham travel to Bolton and Everton are at Hull in four all-Premier League ties.
Tottenham, who lost last season's final 4-1 on penalties to United at Wembley, are away to Preston.
There is a chance of an upset at Carlisle, where the League One team entertain Portsmouth, while Stoke entertain Championship club Blackpool, who shocked Wigan in the last round.
Third round draw
Arsenal vs West Brom; Chelsea vs QPR; Bolton vs West Ham; Barnsley vs Burnley; Hull City vs Everton; Leeds vs Liverpool; Manchester United vs Wolves; Manchester City vs Fulham; Sunderland vs Birmingham City; Peterborough vs Newcastle; Carlisle vs Portsmouth; Notts F. vs Blackburn Rovers; Stoke City vs Blackpool; Scunthorpe vs Port Vale; Preston NE vs Tottenham; Aston Villa vs Cardiff City.
Ties to be played week commencing September 21.