Juventus's Leonardo Bonucci scored a valuable away goal in the 85th minute to snatch a 1-0 win over Olympique Lyon in their Europa League quarter-final and Basel, Porto and Benfica also grabbed first-leg victories.
Swiss side Basel took a huge step towards a second successive Europa League semi-final as Matias Delgado scored twice and Valentin Stocker netted a third in injury time in a 3-0 win over Valencia.
Porto and Benfica capped a good night for the Portuguese with 1-0 wins over Sevilla and AZ Alkmaar respectively.
Eliaquim Mangala scored with a header in the 31st minute for Porto at home to Spanish side Sevilla while Salvio volleyed home three minutes after halftime to give Benfica victory in the Netherlands.