Australian doctors yesterday hailed what they described as a world-first surgical treatment for a boy suffering from a rare disease that sends his blood pressure soaring and triggered a stroke.

Matthew Gaythorpe, 10, has suffered severe hypertension his entire life due to a combination of kidney and liver conditions called auto-somal recessive polycystic kidney disease and congenital hepatitic fibrosis.

He had a minor stroke last year and has lived with seizures and extreme fatigue requiring him to take about 30 medications a day.

He was also diagnosed, at age four, with the chronic sleep disorder narcolepsy.

Matthew was facing the prospect of daily dialysis, a dual kidney-liver transplant and even another stroke until his doctor was specially allowed to try a highly experimental operation with a custom-made device.

“Using innovative radio frequency technology, we were able to effectively zap some of the nerves and tissue surrounding Matthew’s renal arteries,” said surgeon Ian Meredith from the Monash Heart institute.

“This has resulted in a noticeable reduction in Matthew’s symptoms and blood pressure.”

Meredith’s plea to try the renal denervation procedure – never before performed on a child and still experimental with adults – went before three separate ethics panels before it was approved.

“We didn’t know whether it was going to work in a child with such a complex set of illnesses,” the surgeon said.

“But on balance we, collectively as a team, came together and felt on compassionate grounds it would be a good thing to do.”

The instrument used, a small balloon with electrodes on its surface, had to be specially designed for keyhole insertion into Matthew’s tiny arteries by an American firm.

Meredith said the “ingenious” device worked by targeting faulty nerves to the kidneys, which are critical in blood pressure control.

Five weeks on Matthew’s mother, Alex Gaythorpe, said there had been a noticeable improvement in her son’s behaviour which she described as now more calm and focused.

“He has begun reading novels again,” she said. “It may seem trivial but (it’s) something he hasn’t been able to do for a while. He is also focusing more at school.”

Gaythorpe said the surgery had given her son a new lease on life.