Floriana will be without defensive duo Emanuel Briffa and Andre Scicluna when they take on Pembroke Athleta.
The Greens, buoyed by their derby win over Valletta, still have an outside chance of leapfrogging Birkirkara into fourth spot so they will be firing on all cylinders again today.
But they will have to do it without Briffa, who must serve a one-match ban following his dismissal against Valletta, and Scicluna, down with ankle trouble.
Pembroke are still in need of points to make sure of their status for a second successive year in the top flight. They already lost twice to the Greens this season in the league.
Midfielder Paltemio Barbetti is out as he starts a two-match ban but winger Leighton Grech is available after recovering from injury.
Previous results: Floriana vs Pembroke 2-1, 4-2.