Roger Federer set up a 24th career meeting against old rival Andy Roddick as both men eased through the Miami Masters second round, but crowd favourite Kim Clijsters crashed out of the women’s event.

Third-seeded Federer, who has a 21-2 record against world number 34 Roddick, recorded his 23rd win of 2012 by beating American wild card Ryan Harrison 6-2, 7-6.

“I felt like I had to win the match like three times at the end, so I was relieved to come through,” Federer said.

“And beating an American in the US is always a big deal, because this is here where they usually play their very best.”

The Swiss superstar is bidding to capture his third Indian Wells-Miami title double, having also won the back-to-back US hardcourt Masters events in 2005 and 2006.

Federer has now won 40 of his past 42 matches since the 2011 US Open semi-finals.

“I guess I’m more confident now. I have been playing really nice as of late,” Federer said.

Top seed Novak Djokovic beat Marcos Baghdatis 6-4, 6-4 to advance to the third round where he will face fellow Serb Viktor Troicki .

Clijsters saved three match points but lost 6-4, 7-6 to Belgian compatriot Yanina Wickmayer in the third round.

Serena Williams breezed into the fourth round with a 6-2, 6-1 win over Italian Roberta Vinci.