Manchester City maintained their imperious start to the season with a fifth straight victory as Bournemouth were swept aside 4-0 to become the latest victims of Pep Guardiola's table-toppers.
Goals from Kevin De Bruyne, Kelechi Iheanacho, Raheem Sterling and Ilkay Guendogan, on his Premier League debut, wrapped up the points after another scintillating display from the title favourites who continue to lay down a marker to their rivals.
Among the chasing pack, Arsenal made it three successive league wins for the first time since January when they eased past 10-man Hull City 4-1 with Alexis Sanchez scoring twice and missing a penalty.
There was also a double strike at Leicester City where new signing Islam Slimani enjoyed a league debut to remember as the champions rediscovered their domestic form to beat Burnley 3-0.
Some pundits predicted Manchester City might suffer during Sergio Aguero's three-match suspension but, after winning the Manchester derby last weekend, they tore into Bournemouth and wasted little time in taking the game away from their opponents.
City were 1-0 up after 15 minutes when loanee Jack Wilshere conceded a free kick on the edge of the area and De Bruyne cleverly fired a set piece beneath the wall and into the net.
They doubled the lead 10 minutes later when Iheanacho stabbed the ball home and the Nigerian then turned provider for Sterling soon after halftime.
Guendogan, who made his first appearance for the club against Borussia Moenchengladbach in the Champions League on Wednesday, rounded off the scoring when he drilled low inside the post.
There was a sour note to come for City when they had Spaniard Nolito sent off for a head-butt with four minutes remaining.
That did little to dampen the spirits of Guardiola, however, who heralded another superb display from Belgium playmaker De Bruyne.
"We are so lucky we have Kevin with us," the coach said. "It was a fantastic performance."
FIRST TASTE
It was a day of superb individual displays with Slimani whetting the appetite of Leicester fans with two goals.
Slimani, who made his debut in the Champions League in midweek after costing a club record 29 million pounds ($37.70 million) last month, was handed his first taste of Premier League action and scored twice in four minutes either side of halftime.
The Algeria striker sneaked between Burnley's centre backs to meet Christian Fuchs' inswinging free kick in first-half stoppage time and then headed home after the break when Riyad Mahrez showcased his dancing feet to shimmy into the box.
Ben Mee's own goal completed the scoring late on as Leicester took their haul to seven points from five games.
Arsenal's season has yet to fully ignite but they made light work of a Hull side who had Jake Livermore sent off for handball in the first half.
Sanchez deflected the ball home to put Arsenal ahead after 17 minutes but the Chilean then fluffed his lines as his penalty was saved by Eldin Jakupovic following Livermore's dismissal.
It was plain sailing from there on in, though, as Theo Walcott doubled the lead 10 minutes into the second half and, although the hosts pulled a goal back from the penalty spot through Robert Snodgrass, there was to be no late fightback.
Sanchez calmed any jitters in the Arsenal ranks when he rifled the ball high into the net and Granit Xhaka made it 4-1 with a bullet finish from distance in stoppage time, putting the London club second in the table on 10 points.
West Bromwich Albion midfielder Nacer Chadli marked a superb home debut with two goals, one a penalty, and two assists as they beat hapless West Ham United 4-2 to hand the Londoners a third straight league defeat.