The artwork has been placed in the eye of a needle and depicts the playwright striking a celebratory pose dressed in a teal tunic and purple stockings, with an Elizabethan-style frame underneath and the words "To see or not to see".

Sculpted out of Kevlar and fragments of cable tie, Wigan used 24-carat gold for the frame around the quote.

It was painted using a floating fibre plucked from the air as a paintbrush, and polished to a shine using microscopic fragments of diamonds.

The tiny Shakespeare, which took four weeks to create, is part of an exhibition of Wigan's work at the Light House Media Centre in Wolverhampton, celebrating key figures from the Midlands.

Wigan, who was born in the city's Wednesfield area, said: "I had to control my heartbeat and the pulse movements in my fingers to create this piece; it took every ounce of my skill and took a lot out of me.

"Like me, Shakespeare was from the Heart of England, and his work made Britain lead the way, culturally, for the whole world.

"When we realised the exhibition would be taking place during the anniversary, the team at Light House asked me to create a special piece and I worked day and night to get it completed.

"Shakespeare is the greatest storyteller the world has ever known, and as I am the world's leading micro-sculptor, I wanted to honour him in the best way I can.

"The most difficult aspect was getting his proportions right, but I am really pleased with the result."

Following the exhibition, which ends on May 2, the piece will be auctioned internationally.

Collectors of Wigan's work include the Queen, Simon Cowell, Sir Elton John and Mike Tyson.

Also on display is the world's smallest sculpture - a motorbike the size of a blood cell, suspended within one of Wigan's own chin hairs.

Shakespeare is believed to have died on his birthday, April 23, in Stratford-upon-Avon in 1616.