Islamic State has claimed responsibility for a car bomb attack at the Italian consulate in Cairo this morning, in an escalation of a Sinai-based insurgency that suggests militants are opening a new front against foreigners in Egypt.

"Through God's blessing, Islamic State soldiers were able to detonate a parked car bomb carrying 450 kg of explosive material on the headquarters of the Italian consulate in central Cairo," the group said on its Twitter account.

"We recommend that Muslims stay clear of these security dens because they are legitimate targets for the mujahideen's strikes."

The bomb killed one person, the Egyptian health ministry and security officials said.

State news agency MENA cited a senior security source as saying preliminary investigations indicated that a bomb was placed under a car near the consulate and remotely detonated. 

The identity of the person killed was not immediately clear but he was not Italian. A health ministry spokesman said four civilians were wounded. MENA separately said two policemen were among the wounded.

Italy's Foreign Minister Paolo Gentiloni said there were no Italian victims in the blast. "Italy will not be intimidated," he said on Twitter.

Islamist militants have carried out roadside bomb attacks and suicide bombings which have so far targeted members of the security forces and officials.

Hundreds of soldiers and police have been killed since the army toppled Islamist President Mohamed Mursi in 2013 following mass protests against his rule.

Egypt has witnessed a recent increase in attacks against tourism targets, including a suicide bombing near the ancient Karnak temple in Luxor last month.

An attack on Westerners could signal a dangerous escalation of violence in the country, which is relatively stable in a region engulfed by militancy and sectarian conflict since the Arab Spring uprisings.

A Western diplomat said he was aware of the explosion in front of the consulate but could not confirm that the building was the target.

The violence, and political turmoil triggered by the 2011 revolt that toppled autocrat Hosni Mubarak, have hurt Egypt's tourism industry and economy.

Two weeks ago, a car bomb killed the country's top public prosecutor and militants affiliated to Islamic State attacked several military checkpoints in North Sinai, in what was the fiercest fighting in the region in years.

The army said 17 soldiers and more than 100 militants were killed in those clashes.

President Abdel Fattah al-Sisi says militants poses a grave threat to Egypt. But military operations in the Sinai, the epicentre of an insurgency led by Islamic State's Egyptian affiliate, have failed to defeat militants there.

Western countries are hoping Sisi can maintain relative stability in the Arab world's most populous country, in a region beset by turmoil.

Sign up to our free newsletters

Get the best updates straight to your inbox:
Please select at least one mailing list.

You can unsubscribe at any time by clicking the link in the footer of our emails. We use Mailchimp as our marketing platform. By subscribing, you acknowledge that your information will be transferred to Mailchimp for processing.