Serena Williams powered past big sister Venus to reach her 11th Wimbledon quarter-final yesterday, while best friend Caroline Wozniacki’s wait for a place in the last eight at SW19 goes on.

Top seed Williams extended her quest for that elusive calendar Grand Slam by swatting aside elder sister Venus 6-4 6-3, but Wozniacki tumbled out, dispatched by Spain’s Garbine Muguruza.

Fifth seed Wozniacki slipped out 6-4 6-4 to the world number 20, losing in Wimbledon’s fourth round for the fifth time in her career.

This was the Williams siblings’ first Wimbledon meeting in six years, some 17 years after the two five-time SW19 champions’ first professional meeting.

Perhaps Serena spoiled Venus’ best remaining chance for an eighth major title, the elder Williams already 35 and having suffered previously from auto-immune disease Sjogren’s syndrome.

Serena Williams will now square up to Victoria Azarenka in the quarter-finals after the 23rd seed eased past Eastbourne winner Belinda Bencic 6-2 6-3.

At 33, Serena Williams will cement her place in tennis immortality should she add two more majors to her current haul of 20 between now and the end of the year, to complete that calendar slam.

The younger Williams admitted family ties are always put aside when the inseparable sisters meet on court.

“It’s hard to go up against someone you root for all the time no matter what, who you love and is your best friend in the world,” said Serena.

“So it’s never easy, but you just play for the competition and enjoy the moment.

“I think I served well today, I didn’t hit huge serves, I hit one big serve and other than that I think I was really consistent with my serve.

“She was playing really well, but in the end I was able to come through.”

Danish player Wozniacki’s conqueror Muguruza will face Timea Bacsinszky in the last eight after the 15th seed recovered from a faltering start to move past Monica Niculescu 1-6 7-5 6-2.

America’s Madison Keys also needed three sets to reach the last eight, seeing off Olga Govortsova 3-6 6-4 6-1 to book a tussle with 13th seed Agnieska Radwanska.

The former Wimbledon finalist, who split with coach Martina Navratilova earlier this year, saw off Jelena Jankovic 7-5 6-4.

Maria Sharapova will face America’s Coco Vandeweghe, the Russian fourth seed moving past Zarina Diyas 6-4 6-4.

Vandeweghe upset sixth seed and French Open finalist Lucie Safarova 7-6 7-6 to book that battle with 2004 Wimbledon winner Sharapova.

In the men’s tournament, Andy Murray overcame a giant obstacle to keep his dream of a second Wimbledon title alive as he fought his way into the quarter-finals.

The 28-year-old needed three hours and three minutes to beat 6ft 10in Ivo Karlovic, the tallest player on the men’s tour, 7-6 6-4 5-7 6-4.

He will now face Canada’s Vasek Pospisil who reached his first grand slam quarter-final by upsetting Viktor Troicki on Court 12, fighting back from two sets behind to oust the Serbian 22nd seed 4-6 6-7 6-4 6-3 6-3.

Federer momentum

Roger Federer‘s pursuit of an 18th grand slam title gathered momentum as the Swiss reached his 45th major quarter-final with a serene 6-2 6-2 6-3 victory over Spaniard Roberto Bautista Agut.

Federer plays next France’s Gilles Simon who was a surprisingly comfortable 6-3 6-3 6-2 victor against Czech sixth seed Tomas Berdych, while Croatia’s US Open champion Marin Cilic reached the last-eight stage with a 6-4 4-6 6-3 7-5 win against American Denis Kudla.

Richard Gasquet took advantage of a Wimbledon strop from Nick Kyrgios to avenge last year’s second-round defeat to the Australian and reach the quarter-finals.

The Court Two crowd booed Kyrgios as he appeared to deliberately lose the third game of the second set, with the 20-year-old having been riled at being handed a code violation for swearing by umpire James Keothavong.

He showed only slightly more appetite for the rest of the second set, and went on to lose the match 7-5 6-1 6-7 7-6.

Latest result: Djokovic vs Anderson 6-7 6-7 6-1 6-4 (match to resume today).