Milan have enjoyed a perfect start to the season, but coach Filippo Inzaghi believes it will take a “miracle” for his side to beat defending champions Juventus tonight.
The Rossoneri have won their opening two games and are level on six points with Juve and Roma at the top of the Serie A table.
“We have nothing to lose because they are stronger, but in football you never know,” Inzaghi said.
“I hope the San Siro and our fans can help us achieve a miracle.”
Juve, who have not conceded a goal since April 28 in all competitions, are looking to end another successful week on a high note.
Carlos Tevez scored twice as Juve beat Malmo 2-0 in their Champions League opener in Turin on Tuesday.
The result followed a 2-0 triumph over Udinese and continued Massimiliano Allegri’s winning start to life as Juve coach.
Allegri joined the Turin giants this summer, six months after being dismissed by Milan.
Roma also got off to a winning start in the Champions League, rolling to a 5-1 triumph over CSKA Moscow on Wednesday.
The Romans host winless Cagliari tomorrow.
Inter go into their clash at Palermo on the back of a 1-0 triumph at Dnipro in their Europa League opener. The result in Ukraine followed their 7-0 demolition of Sassuolo, their first win of the campaign.
Fiorentina tasted victory for the first time in the 2014-15 season by prevailing 3-0 over Guingamp on Thursday in the Europa League.
The Viola had taken just one point from their first two Serie A games and take on unbeaten Atalanta in Bergamo.
Napoli were the other Italian side to win in the Europa League as they beat Sparta Prague 3-1 at the San Paolo. Napoli, who lost 1-0 at home to Chievo last weekend, take on Udinese at the Friuli stadium.
Torino claimed a point in a goalless draw at Club Brugge in their Europa League game.
Toro are back playing in European football for the first time in 20 years.
The Turin side host Verona tomorrow evening.
Chievo are hoping to build on their surprise victory at Napoli when they face Parma.
Sassuolo must overcome the absence of suspended Domenico Berardi when they host Sampdoria.
Striker Berardi will begin a three-match ban as his punishment for elbowing Inter’s Juan Jesus.
Lazio are aiming for a second consecutive win. After beating Cesena, they face Genoa away.
Fixtures
Serie A
Playing today
Cesena vs Empoli - 18.00
Milan vs Juventus - 20.45
Tomorrow – 15.00
Atalanta vs Fiorentina - 18.00
Chievo vs Parma - 12.30
Genoa vs Lazio
Roma vs Cagliari
Sassuolo vs Sampdoria
Palermo vs Inter - 20.45
Torino vs Verona - 20.45
Udinese vs Napoli - 18.00
Standings: Milan, Juventus, Roma 6; Inter, Sampdoria, Atalanta, Verona 4; Lazio, Napoli, Udinese, Chievo, Cesena 3; Cagliari, Palermo, Genoa, Fiorentina, Torino, Sassuolo 1; Parma, Empoli 0.
Serie B
Carpi vs Trapani - 2-2
Spezia vs Entella - 1-0
Today – 15.00
Bari vs Livorno
Bologna vs Crotone
Brescia vs Ternana
Catania vs Modena
Cittadella vs Pescara
Latina vs Avellino
Perugia vs Vicenza
Pro Vercelli vs Varese
Lanciano vs Frosinone
Monday
Spezia vs Carpi 20.30
Leading standings: Perugia 9; Trapani 8; Ternana, Spezia 7; Carpi 6; Lanciano, Livorno, Latina 5.