A tournament-ending knee injury to American John Isner yesterday handed Spain a berth in this weekend’s final of the Hopman Cup.

The US pairing of Isner and Venus Williams were set to face Spain’s Fernando Verdasco and Anabel Medina Garrigues yesterday, with the winner to progress to tomorrow’s final.

However, Isner withdrew from the tournament yesterday morning citing a right knee problem, handing Spain a 3-0 victory and passage into the final for the sixth time.

Spain have won the mixed teams title three times, most recently in 2010, when Tommy Robredo and Maria Jose Martinez Sanchez lifted the title against Great Britain’s Laura Robson and Andy Murray.

“We are happy, of course, to be in the final,” Verdasco said.

“It was going to be a difficult tie today, but when John didn’t play, it is unlucky for everybody, but we are in the final and hopefully it is going to be a good day for us.”

Spain will face Serbian top seeds Novak Djokovic and Ana Ivanovic or Australian surprise packets Bernard Tomic and Ashleigh Barty in the final, with the former expected to earn their place in the play-off by beating winless Germany today.

The host nation stayed in contention for the final by beating Italy in yesterday’s evening tie.

Isner looked troubled by his right knee in both his singles matches for the United States this week, losing in straight sets to South Africa’s Kevin Anderson and France’s Jo-Wilfried Tsonga.

Speaking after his withdrawal, the towering American said he expected to be fit for the Australian Open, starting on Monday week in Melbourne, despite being unsure of the exact nature of the injury.

“I’ve always been a fast healer when I have had real injuries pop up here and there so I’m confident I’m going to be fine for the Australian Open,” he said.

The withdrawal of Isner, who won the event in 2011 with Bethanie Mattek-Sands, ended Venus Williams’ hopes of joining her sister, Serena, as a Hopman Cup winner.

“I feel like I let her down a little bit,” Isner said.

The evening tie saw Australia beat Italy 2-1 to stay in the hunt for the final, although they need Germany to upset Serbia today.

Tomic, 20, backed up his shock win over Djokovic the previous night by beating Andreas Seppi 6-3, 7-5, converting the only two break points he held during the match.

Sixteen-year-old Ashleigh Barty then stunned former French Open champion Francesca Schiavone with an imperious 6-0, 6-3 win.

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