Ireland has given a resounding endorsement to tough new budget controls under the European fiscal treaty.
Official referendum figures declared at the Dublin Castle count centre showed the controversial pact was backed by a margin of 326,003 votes, or 60.3% in favour.
Five of Ireland's 43 constituencies rejected the plan including both electoral regions of Donegal and three others in Dublin, one of which is home to two ministers.
Returning officer Riona Ni Flanghaile announced a total of 955,091 votes in favour compared with 629,088 against the agreement.
Among the first messages to Europe after voter support was secure, Tanaiste Eamon Gilmore, Ireland's deputy prime minister, said the country now needs a deal on its bank debt.
"I think this decision taken by the Irish people is a necessary step on the road to recovery but we now have to build on it," he said.
"This was not just an exercise ... asking people to vote Yes - it was also an occasion where we listened to what people where saying."
The Tanaiste, whose Dun Laoghaire constituency south of Dublin saw the second highest support for the treaty, added: "We do need to have a deal in relation to our bank debt. We do need to see progress upon it."
Sinn Fein president Gerry Adams warned that the Government will be tackled harder now on whether it can meet commitments to ease the pressure of austerity.
"The Government has given firm commitments in terms of committing on a bank bailout, in terms of growth and jobs incentive initiatives so we will be holding the Government to those promises.
"The problems which are facing people today will be there tomorrow.
"Clearly an element of the Yes vote was ideologically committed to the Yes camp and others did so very, very reluctantly."
In his first response to the resounding victory, Taoiseach Enda Kenny said Ireland's bank debt must be included in future discussions to revive the wider European economy.
"The Irish people have sent a powerful signal around the world that this is a country serious about overcoming our economic challenges," he said.
"The treaty will not solve all economic problems but it is a foundation stone to make sure the economy stands on firm ground."
The Taoiseach said the result would help bring stability and credibility and ensure Ireland has access to funding under the European Stability Mechanism (ESM) if needed.
In an address on the steps of Government Buildings, and flanked by his deputy Tanaiste Eamon Gilmore, Mr Kenny insisted that the country's crippling bank bailout should not be detached from any talks on rescuing the economy.
"Ireland's banking debt must form part of that solution," he said.