Federer stunned by Canas on day of upsets

World number one Roger Federer suffered a stunning 7-5 6-2 upset defeat by Argentine Guillermo Canas in the Pacific Life Open second round.

Former world number ones Lleyton Hewitt and Marat Safin also bowed out, the former losing 7-6 4-6 6-2 to Serb Janko Tipsarevic and Russian Safin going down 6-3 4-6 6-0 to Frenchman Nicolas Mahut.

Briton Andy Murray, the last man to beat Federer, reached the third round, however, along with Australian Open runner-up Fernando Gonzalez and eighth seed Ivan Ljubicic.

Federer, seeking his fourth Indian Wells Masters Series title in a row, received treatment for blisters at the end of the first set and looked sluggish throughout as his 41-match winning streak was ended by the world number 60.

The Swiss ten-times grand slam champion, whose last defeat was inflicted by Murray in Cincinnati in August, was hoping to break the professional era record of 46 successive wins set by Argentine Guillermo Vilas.

Federer said the pressure of closing on another record had not contributed to his defeat.

"It's no pressure at all because I take it match by match," Federer told reporters.

"It just shows you how tough it is. Today was just a grind for me from the start. First-round match is always difficult, but I've had an incredible run, not losing in the first round for over two years. So I'm really happy about that. Sooner or later it had to happen, so it's OK."

Federer celebrated his 161st consecutive week as world number one last month, breaking the 30-year-old record of American Jimmy Connors.

"It's great to beat the number one, I feel perfect," the 29-year-old Canas told reporters. "I dream about this, but I didn't expect it. I have confidence in my game but I know it's going to be tough."

Canas, who achieved his career-high ranking of eighth in 2005, returned to the tour last September after serving a 15-month suspension for a doping offence.

He lost in last round of qualifying for the tournament to German Alexander Waske, but earned a place in the draw when Belgium's Xavier Malisse withdrew due to injury.

Murray, seeded 13th, eased past South African Wesley Moodie 6-3 6-3 to reach the third round.

The British number one, winner in San Jose this year, next faces Mahut who upset 23rd seed Safin.

Spanish seventh seed Tommy Robredo lost to Gilles Simon of France 6-7 6-3 6-0, and number 17 Marcos Baghdatis of Cyprus went down 7-5 7-5 to Guillermo Garcia-Lopez of Spain.

Fifth seed Gonzalez of Chile and Nalbandian advanced to the third round with three-set victories over Canadian Frank Dancevic and German Philipp Kohlschreiber respectively. Ljubicic struggled past Colombian Alejandro Falla 6-7 6-4 6-4.

Rusty Sharapova, Hingis advance

Top seed Maria Sharapova overcame sloppy serving and brutal heat to beat Frenchwoman Nathalie Dechy 7-5 6-2 and reach the Pacific Life Open fourth round.

Third seed Martina Hingis also advanced with a 6-2 6-4 victory over Austria's Yvonne Meusburger.

Sharapova next faces compatriot and number 15 seed Vera Zvonareva who defeated Victoria Azarenka 6-3 6-3.

Former world number one Hingis will next face number 14 Daniela Hantuchova, who fought past Francesca Schiavone of Italy 6-2 7-6.

Seventh seed Jelena Jankovic of Serbia beat Martina Muller 6-2 6-4, and eighth seed Anna Chakvetadze of Russia overcame compatriot Maria Kirilenko 6-4 6-1.

Number 11 Shahar Peer of Israel overcame a determined challenge from Lucie Safarova of the Czech Republic to win 6-3 1-6 6-4, and Li Na of China defeated Alona Bondarenko of Russia 5-7 6-3 6-2.